Publication: Fungemia: Updates on the Detection Methods, Causative Agents and Treatments
| dc.contributor.author | Dr Sayaphet Rattanavong | |
| dc.date.accessioned | 2024-06-25T05:40:31Z | |
| dc.date.available | 2024-06-25T05:40:31Z | |
| dc.date.issued | 2011 | |
| dc.description | iv, 34 pages: illustrations, table 31cm | |
| dc.description.abstract | Fungi are extremely beneficial microorganisms. In nature, they decompose dead organisms particularly plants to recycle their nutrient. In vascular plants, about 90%, form mycorrhizae at their roots which are beneficial associations with fungi that assist the plants to absorb water and dissolved minerals. Human uses fungi for food and in manufacture of foods and beverages, including bread, alcoholic beverages, citric acid, soy sauce and some cheese. In medical application, fungi also produce antibiotics such as penicillin and cephalosporin; the immunosuppressive drug cyclosporine which makes organ transplants possible (Bauman, 2009). However, some fungi live on human skin or mouth, several are pathogenic to man and may cause a wide range of disease, from superficial involvement of skin, hair or nail or mucous membrane, to involvement of subcutaneous tissue, to localized disseminated invasion of the body 'Systemic mycosis' (Mandal et al,, 2004). The circular system, consist of the blood, blood vessels, and the heart, is normally free of microbial organism so the isolation of bacterial or fungi from the blood of ill patient usually signifies serious; ncontrolled infection that may result in severe sepsis and sepsis shock which are the leading cause of death, particularly in intensive care units worldwide and account for 2-11% of all hospital or ICU admission in the USA and Europe. The incidence of blood stream infection has increased in recent decades because of the growth in: intensive care management, immunesuppressed population, and elderly population, population living longer with chronic disease, intravenous drug misuse and microbial resistance (Baron, 1996; Mandal et al., 2004), Report of nosocomial blood stream infection in 49 US hospitals over 7-years period had shown that most cases are caused by gram-positive organism (65%), gram- negative organism (25%) and fungi (9.5% the rank order of the major pathogens shows that candida species was regarded as the fourth most frequent cause of blood stream infection. Furthermore, among candida isolates C albicans was the most common (54%) follow by C glabrata (19%), C. parapsilosis (I%) and C tropicalis (11%) (Wisplinghoff et al., 2004). | |
| dc.identifier.uri | https://repository.nih.gov.my/handle/123456789/386 | |
| dc.identifier.uri | https://library.nih.gov.my/e-doc/flipbook/thesis/dmm/760-761-762/index.html | |
| dc.language.iso | en | |
| dc.publisher | Kuala Lumpur: Institute for Medical Research | |
| dc.subject | Dissertations Academic--Malaysia | |
| dc.subject | Mycoses--Dissertations | |
| dc.title | Fungemia: Updates on the Detection Methods, Causative Agents and Treatments | |
| dc.type | text::thesis | |
| dspace.entity.type | Publication | |
| oairecerif.author.affiliation | #PLACEHOLDER_PARENT_METADATA_VALUE# |