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Association of BMI with risk of CVD mortality and all-cause mortality

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dc.contributor.authorChee Cheong Kee
dc.contributor.authorMohd Ghazali Sumarni
dc.contributor.authorKuang Hock Lim
dc.contributor.authorSharmini Selvarajah
dc.contributor.authorJamaiyah Haniff
dc.contributor.authorGuat Hiong Helen Tee
dc.contributor.authorKaur Gurpreet
dc.contributor.authorYusoff Ahmad Faudzi
dc.contributor.authorNasir Mustafa Amal
dc.date.accessioned2024-08-06T13:37:01Z
dc.date.available2024-08-06T13:37:01Z
dc.date.issued2017
dc.description.abstractObjective To determine the relationship between BMI and risk of CVD mortality and all-cause mortality among Malaysian adults. Design Population-based, retrospective cohort study. Participants were followed up for 5 years from 2006 to 2010. Mortality data were obtained via record linkages with the Malaysian National Registration Department. Multiple Cox regression was applied to compare risk of CVD and all-cause mortality between BMI categories adjusting for age, gender and ethnicity. Models were generated for all participants, all participants the first 2 years of follow-up, healthy participants, healthy never smokers, never smokers, current smokers and former smokers. Setting All fourteen states in Malaysia. Subjects Malaysian adults (n 32 839) aged 18 years or above from the third National Health and Morbidity Survey. Results Total follow-up time was 153 814 person-years with 1035 deaths from all causes and 225 deaths from CVD. Underweight (BMI<18·5 kg/m2) was associated with a significantly increased risk of all-cause mortality, while obesity (BMI ≥30·0 kg/m2) was associated with a heightened risk of CVD mortality. Overweight (BMI=25·0–29·9 kg/m2) was inversely associated with risk of all-cause mortality. Underweight was significantly associated with all-cause mortality in all models except for current smokers. Overweight was inversely associated with all-cause mortality in all participants. Although a positive trend was observed between BMI and CVD mortality in all participants, a significant association was observed only for severe obesity (BMI≥35·0 kg/m2). Conclusions Underweight was associated with increased risk of all-cause mortality and obesity with increased risk of CVD mortality. Therefore, maintaining a normal BMI through leading an active lifestyle and healthy dietary habits should continue to be promoted.
dc.identifier.doihttps://doi.org/10.1017/S136898001600344X
dc.identifier.urihttps://www.cambridge.org/core/journals/public-health-nutrition/article/association-of-bmi-with-risk-of-cvd-mortality-and-allcause-mortality/FCE1835D155FC7C77F485396EE1E8C68
dc.identifier.urihttps://repository.nih.gov.my/handle/123456789/852
dc.language.isoen
dc.publisherCambridge University Press
dc.relation.ispartofPublic Health Nutrition
dc.relation.issn1475-2727
dc.relation.journalPublic Health Nutrition
dc.subjectBMI
dc.subjectCVD
dc.subjectMortality
dc.subjectObesity
dc.subjectOverweight
dc.titleAssociation of BMI with risk of CVD mortality and all-cause mortality
dc.typejournal-article
dspace.entity.typePublication
oaire.citation.issue7
oaire.citation.volume20
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