Publication:
Effects of Vegetarian Diets on Blood Pressure Lowering: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Simple item page
dc.contributor.authorKai Wei Lee
dc.contributor.authorHong Chuan Loh
dc.contributor.authorSiew Mooi Ching
dc.contributor.authorNavin Kumar Devaraj
dc.contributor.authorFan Kee Hoo
dc.date.accessioned2024-08-22T03:35:55Z
dc.date.available2024-08-22T03:35:55Z
dc.date.issued2020
dc.description.abstractThe beneficial effects of a vegetarian diet on blood pressure (BP) control have been reported in previous systematic reviews; however, so far, their relative effectiveness is not well established. Here, we performed a systematic review together with trial sequential analysis to determine the effect of a vegetarian diet on the reduction of blood pressure. We searched the randomized controlled trial (RCT) through Medline, PubMed and Cochrane Central Register. Fifteen eligible RCTs with 856 subjects were entered into the analysis. The pooled results demonstrated that vegetarian diet consumption significantly lowered the systolic blood pressure (weighted mean difference (WMD), −2.66 mmHg (95% confidence interval (CI) = −3.76, −1.55, p < 0.001) and diastolic BP was WMD, −1.69 95% CI = −2.97, −0.41, p < 0.001) as compared to an omnivorous diet. In subgroup analysis, a vegan diet demonstrated a greater reduction in systolic BP (WMD, −3.12 mmHg; 95% CI = −4.54, −1.70, p < 0.001) as compared with a lacto-ovo-vegetarian diet (WMD, −1.75 mmHg, 95% CI −5.38, 1.88, p = 0.05). The vegan diet has showed a similar trend in terms of diastolic blood pressure reduction (WMD, −1.92 mmHg (95% CI = −3.18, −0.66, p < 0.001) but those with a lacto-ovo-vegetarian diet showed no changes in diastolic BP reduction (WMD, 0.00, 95% CI = 0.00, 0.00), p = 0.432). In conclusion, vegetarian diets are associated with significant reductions in BP compared with omnivorous diets, suggesting that they may play a key role in the primary prevention and overall management of hypertension.
dc.identifier.doi10.3390/nu12061604
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/32486102/
dc.identifier.urihttps://repository.nih.gov.my/handle/123456789/985
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofNutrients
dc.relation.issn2072-6643
dc.relation.journalNutrients
dc.subjectHypertension
dc.subjectDiet
dc.subjectVegan
dc.subjectVegetarian
dc.subjectPlant‐based diets
dc.titleEffects of Vegetarian Diets on Blood Pressure Lowering: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
dc.typejournal-article
dspace.entity.typePublication
oaire.citation.endPage17
oaire.citation.issue6
oaire.citation.startPage1
oaire.citation.volume12
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
NIH20200215.pdf
Size:
2.1 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Selected Article of Journal (ICR)