Surgery has been defined as a science or arte that sheweth the manner how to work on man's body excercising all manuall aperation necessary to heal man or as musch as is possible by using of most expedient medicines.Unfortunately infection has become a major cause of post operative mortality and morbidity, seen since the day surgery began. With the discoveries of Robert Koch in the etiology of infection and Lister with antiseptic, and the aseptic technique developed by Ernst von Bergmann. and early types of vaccine and serotherapy; the more light was shed on the control of post operation infection. Prelisterin accounts of such complication in war and peace were filled with description of hosptal gangrene and other examples that later were recognized as post traumatic and post operative infection.