Browsing by Author "Chandrika Jeevananthan"
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- PublicationCause-specific mortality estimates for Malaysia in 2013: results from a national sample verification study using medical record review and verbal autopsy(2019)
;Azahadi Omar ;Shubash Shander Ganapathy ;Mohamad Fuad Mohamad Anuar ;Yi Yi Khoo ;Chandrika Jeevananthan ;S. Maria Awaluddin ;Jane Ling Miaw YnChalapati RaoBackground: Mortality indicators are essential for monitoring population health. Although Malaysia has a functional death registration system, the quality of information on causes of death still needs improvement, since approximately 30% of deaths are classified to poorly defined causes. This study was conducted to verify registered causes in a sample of deaths in 2013 and utilise the findings to estimate cause-specific mortality indicators for Malaysia in 2013. Methods: This is a cross-sectional study involving a nationally representative sample of 14,497 deaths distributed across 19 districts. Registered causes of deaths were verified using standard medical record review protocols for hospital deaths, and locally adapted international standard verbal autopsy procedures for deaths outside hospitals. The findings were used to measure the validity and reliability of the registration data, as well as to establish plausible cause-specific mortality fractions for hospital and non-hospital deaths, which were subsequently used as the basis for estimating national cause-specific mortality indicators. Results: The overall response rate for the study was 67%. Verified causes of 5041 hospital deaths and 3724 deaths outside hospitals were used to derive national mortality estimates for 2013 by age, sex and cause. The study was able to reclassify most of the ill-defined deaths to a specific cause. The leading causes of deaths for males were Ischaemic Heart Disease (15.4%), Cerebrovascular diseases (13.7%), Chronic Obstructive Pulmonary Disease (8.5%) and Road Traffic Accident (8.0%). Among females, the leading causes were Cerebrovascular diseases (18.3%), Ischaemic Heart Disease (12.7%), Lower Respiratory Infections (11.5%) and Diabetes Mellitus (7.2%). Conclusions: Investigation of registered causes of death using verbal autopsy and medical record review yielded adequate information to enable estimation of cause-specific mortality indicators in Malaysia. Strengthening the national mortality statistics system must be made a priority as it is a core data source for policy and evaluation of the public health and healthcare sectors in Malaysia. - PublicationPremature Mortality among Elderly in Malaysia, 2014(2019)
;Nazirah Alias ;Mohd Azahadi Omar ;Shubash Shander Ganapathy ;Mohamad Fuad Mohamad Anuar ;Chandrika Jeevananthan ;Fazila Haryati AhmadTan Lee AnnIntroduction: Substantial advances on the life expectancy have been achieved in Malaysia over the past few decades. It is essential that elderly lead a healthier old age which leans towards successful aging. Thus, this study describes the major causes of premature mortality among the elderly population in Malaysia, 2014. Methods: The calculation of premature mortality in terms of Years of Life Lost (YLL) was based on the method used in the Global Burden of Disease (GBD) study. YLL is the mortality component determined by the age-sex specific number of deaths and life expectancy at the age of death. Mortality data was obtained from the Department of Statistics Malaysia. Elderly aged 60 years and above were included in this study. Results: The major causes of premature mortality among elderly in Malaysia were Cardiovascular and Circulatory Diseases (39.0%); followed by Malignant Neoplasms (16.6%), Respiratory Diseases (9.8%), Respiratory Infections (9.2%) and Diabetes Mellitus (6.8%). Conclusions: Awareness programme, early screening and help seeking among elderly should be a priority in planning health services to reduce the burden of Non communicable diseases (NCD) among elderly. - PublicationPrevalence of Nonfatal Serious Injury Due to Motor Vehicle Accidents Among Malaysian School-Going Adolescents: Findings From the Adolescent Health Survey 2017(2019)
;S Maria Awaluddin ;Fazila Haryati Ahmad ;Chandrika Jeevananthan ;Shubash Shander Ganapathy ;Rajini Sooryanarayana ;Mohamad Fuad Mohamad Anuar ;Nazirah Alias ;Thamil Arasu Saminathan ;Muhammad Fadhli Mohd YusoffAzriman RosmanSerious injury due to motor vehicle accidents (MVAs) significantly contributes to the adolescents’ health status. The objective of this study was to estimate the prevalence of nonfatal injury due to MVAs and its associated factors among Malaysian school-going adolescents. Nationally representative samples were selected via 2-stage stratified cluster sampling. Data was collected using a validated self-administered questionnaire. Logistic regression analysis was conducted to examine the associations between the variables. A total of 1088 out of 27 497 adolescents reported that they had sustained serious injury due to MVAs with a prevalence of 4.1% (95% confidence interval [CI] = 3.7-4.5). Serious injury due to MVAs among adolescents was positively associated with being current cigarette smokers (adjusted odds ratio [aOR] = 2.5; 95% CI = 2.2-2.9), followed by Malay ethnicity (aOR = 2.4; 95% CI = 1.9-3.0), current drug users (aOR = 2.3; 95% CI = 1.9-3.0), boys (aOR = 2.1; 95% CI = 1.8-2.4), Indian ethnicity (aOR = 1.8; 95% CI = 1.2-2.5), and those who were in upper secondary school (aOR = 1.3; 95% CI = 1.2-1.5). Targeted intervention and curbing substance use among boys may reduce the morbidities from MVAs and its resulting complications. - PublicationValidation of verbal autopsy: determination of cause of deaths in Malaysia 2013(2017)
;Shubash Shander Ganapathy ;Khoo Yi Yi ;Mohd Azahadi Omar ;Mohamad Fuad Mohamad Anuar ;Chandrika JeevananthanChalapati RaoBackground: Mortality statistics by age, sex and cause are the foundation of basic health data required for health status assessment, epidemiological research and formation of health policy. Close to half the deaths in Malaysia occur outside a health facility, are not attended by medical personnel, and are given a lay opinion as to the cause of death, leading to poor quality of data from vital registration. Verbal autopsy (VA) is a very useful tool in diagnosing broad causes of deaths for events that occur outside health facilities. This article reports the development of the VA methods and our principal finding from a validation study. Methods: A cross sectional study on nationally representative sample deaths that occurred in Malaysia during 2013 was used. A VA questionnaire suitable for local use was developed. Trained field interviewers visited the family members of the deceased at their homes and conducted face to face interviews with the next of kin. Completed questionnaires were reviewed by trained physicians who assigned multiple and underlying causes. Reference diagnoses for validation were obtained from review of medical records (MR) available for a sample of the overall study deaths. Results: Corresponding MR diagnosis with matched sample of the VA diagnosis were available in 2172 cases for the validation study. Sensitivity scores were good (>75%) for transport accidents and certain cancers. Moderate sensitivity (50% - 75%) was obtained for ischaemic heart disease (64%) and cerebrovascular disease (72%). The validation sample for deaths due to major causes such as ischaemic heart disease, pneumonia, breast cancer and transport accidents show low cause-specific mortality fraction (CSMF) changes. The scores obtained for the top 10 leading site-specific cancers ranged from average to good. Conclusion: We can conclude that VA is suitable for implementation for deaths outside the health facilities in Malaysia. This would reduce ill-defined mortality causes in vital registration data, and yield more accurate national mortality statistics.